Preheat oven to 350 degrees F.
Whisk together flour, baking soda, salt, and spice in a small bowl; set aside.
Beat butter, granulated sugar, brown sugar, egg, and vanilla extract together in a large bowl until light and fluffy.
Gradually add the flour mixture, stir until just combined.
Stir in oats and butterscotch chips.
Drop by rounded Tablespoonfuls (about 2 tablespoons of dough) onto an ungreased baking sheet.
Bake 14 to 16 minutes or until deep golden brown
Cool on baking sheets for 2 minutes, remove to wire racks to cool completely.